4-Bromomethyl-2-chloro-5-iodo-pyridine → N-(2-Chloro-5-iodo-pyridin-4-ylmethyl)-N-(4-chloro-2-vinyl-phenyl)-acetamide

HRID 1539450Notes

Reaction equation

HRID 1539450 reaction equation
[Br:11][c:12]1[cH:13][c:14]([CH2:15][N:20]([C:21]([CH3:22])=[O:23])[c:24]2[c:25]([CH:31]=[CH2:32])[cH:26][c:27]([Cl:30])[cH:28][cH:29]2)[c:16]([Cl:17])[n:18][cH:19]1.[Br:1][CH2:2][c:3]1[cH:4][c:5]([Cl:10])[n:6][cH:7][c:8]1[I:9].[Cl:33][c:34]1[c:35]([CH2:36][N:37]([c:38]2[cH:39][cH:40][cH:41][cH:42][c:43]2[CH:44]=[CH2:45])[C:46](=[O:47])[CH3:48])[cH:49][c:50]([F:51])[c:52]([Cl:53])[n:54]1>>[CH2:2]([c:3]1[cH:4][c:5]([Cl:10])[n:6][cH:7][c:8]1[I:9])[N:20]([C:21]([CH3:22])=[O:23])[c:24]1[c:25]([CH:31]=[CH2:32])[cH:26][c:27]([Cl:30])[cH:28][cH:29]1

Participants

4

Reactant 3

HCID 597175634-Bromomethyl-2-chloro-5-iodo-pyridineHCID 59717570N-(2,6-dichloro-5-fluoro-pyridin-3-ylmethyl)-N-(2-vinyl-phenyl)-acetamideHCID 59717599N-(5-Bromo-2-chloro-pyridin-3-ylmethyl)-N-(4-chloro-2-vinyl-phenyl)-acetamide

Product 1

HCID 59717576N-(2-Chloro-5-iodo-pyridin-4-ylmethyl)-N-(4-chloro-2-vinyl-phenyl)-acetamide

Sources & evidence

ORD record
ord-5e560a02f781457b812b541f48ed6f83
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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