2-Chloro-5-(chloromethyl)pyridine → 1'-((6-chloropyridin-3-yl)methyl)-6H-spiro[benzofuro[6,5-d][1,3]dioxole-7,3'-indolin]-2'-one

HRID 1540000Notes

Reaction equation

HRID 1540000 reaction equation
[Br:10][CH2:11][c:12]1[o:13][c:14]([C:15]([F:16])([F:17])[F:18])[cH:19][cH:20]1.[CH3:42][C:43]1([CH3:44])[CH2:45][O:46][c:47]2[cH:48][c:49]3[c:62]([cH:63][c:64]21)[C:52]1([CH2:51][O:50]3)[c:53]2[c:54]([cH:55][cH:56][cH:57][cH:58]2)[NH:59][C:60]1=[O:61].[Cl:1][c:2]1[n:3][cH:4][c:5]([CH2:8][Cl:9])[cH:6][cH:7]1.[NH:21]1[C:22](=[O:41])[C:23]2([CH2:24][O:25][c:26]3[c:27]2[cH:28][c:29]2[c:30]([cH:34]3)[O:31][CH2:32][O:33]2)[c:35]2[cH:36][cH:37][cH:38][cH:39][c:40]21>>[Cl:1][c:2]1[n:3][cH:4][c:5]([CH2:8][N:21]2[C:22](=[O:41])[C:23]3([CH2:24][O:25][c:26]4[c:27]3[cH:28][c:29]3[c:30]([cH:34]4)[O:31][CH2:32][O:33]3)[c:35]3[cH:36][cH:37][cH:38][cH:39][c:40]32)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 1554792-Chloro-5-(chloromethyl)pyridineHCID 27946052-(Bromomethyl)-5-(trifluoromethyl)furanHCID 53375495spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-oneHCID 592634705,5-dimethyl-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3'-indol]-2'(1H)-one

Product 1

HCID 592634431'-((6-chloropyridin-3-yl)methyl)-6H-spiro[benzofuro[6,5-d][1,3]dioxole-7,3'-indolin]-2'-one

Sources & evidence

ORD record
ord-884cf2db534e48489acf5e6dce6f5f12
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…