Acetic Acid → 2-(N-benzyloxycarbonylpiperidin-4-yl-methyl)amino-5-chloro-alpha-(3-tert-butoxycarbonylaminomethylphenyl)benzyl alcohol
Reaction equation
[BH4-:23].[C:24]([Na:25])#[N:26].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][CH:14]([CH:17]=[O:18])[CH2:15][CH2:16]1.[CH3:19][C:20](=[O:21])[OH:22].[CH3:52][OH:53].[NH2:27][c:28]1[c:29]([CH:30]([c:31]2[cH:32][c:33]([CH2:37][NH:38][C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[cH:34][cH:35][cH:36]2)[OH:46])[cH:47][c:48]([Cl:51])[cH:49][cH:50]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][CH:14]([CH2:17][NH:27][c:28]2[c:29]([CH:30]([c:31]3[cH:32][c:33]([CH2:37][NH:38][C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[cH:34][cH:35][cH:36]3)[OH:46])[cH:47][c:48]([Cl:51])[cH:49][cH:50]2)[CH2:15][CH2:16]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-9034480112664e56b13293a6657acc52
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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