tert-Butyl acetate → 3-[3-(2,4-Dimethyl-imidazol-1-yl)-phenyl]-3-oxo-propionic acid tert.-butyl ester

HRID 1540811Notes

Reaction equation

HRID 1540811 reaction equation
[C:19]([CH3:20])(=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26].[CH3:1][c:2]1[n:3](-[c:8]2[cH:9][c:10]([C:11]([O:13][CH2:12][CH3:14])=[O:15])[cH:16][cH:17][cH:18]2)[cH:4][c:5]([CH3:7])[n:6]1.[Li:27]>>[CH3:1][c:2]1[n:3](-[c:8]2[cH:9][c:10]([C:11](=[O:13])[CH2:20][C:19](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[cH:16][cH:17][cH:18]2)[cH:4][c:5]([CH3:7])[n:6]1

Participants

4

Reactant 3

HCID 10908tert-Butyl acetateHCID 3028194LithiumHCID 22224974Ethyl 3-(2,4-dimethyl-imidazol-1-yl)-benzoate

Product 1

HCID 695928063-[3-(2,4-Dimethyl-imidazol-1-yl)-phenyl]-3-oxo-propionic acid tert.-butyl ester

Sources & evidence

ORD record
ord-06707e014abc4d008a93f55857fa58fd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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