1-(Bromomethyl)-4-(difluoromethyl)benzene → 4-chloro-N-[[4-(difluoromethyl)phenyl]methyl]-N-(5,5-difluoro-2-oxoazepan-3-yl)benzenesulfonamide
Reaction equation
[Br:22][CH2:23][c:24]1[cH:25][cH:26][c:27]([CH:30]([F:31])[F:32])[cH:28][cH:29]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[NH:11][CH:12]2[C:13](=[O:21])[NH:14][CH2:15][CH2:16][C:17]([F:19])([F:20])[CH2:18]2)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:11]([CH:12]2[C:13](=[O:21])[NH:14][CH2:15][CH2:16][C:17]([F:19])([F:20])[CH2:18]2)[CH2:23][c:24]2[cH:25][cH:26][c:27]([CH:30]([F:31])[F:32])[cH:28][cH:29]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-e93fedef328140bb8b2a476b915762e4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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