Bicarbonate Ion → Tert-butyl 2-(4-((3-fluoro-5-(trifluoromethyl)benzamido)methyl)piperidin-1-yl)ethylcarbamate

HRID 1541203Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1541203
[CH2:73]1[O:74][CH2:75][CH2:76][CH2:77]1.[CH3:67][CH2:68][O:69][C:70]([CH3:71])=[O:72].[Cl:78][CH2:79][Cl:80].[F:19][c:20]1[cH:21][c:22]([C:23](=[O:24])[OH:25])[cH:26][c:27]([C:29]([F:30])([F:31])[F:32])[cH:28]1.[NH2:1][CH2:2][CH:3]1[CH2:4][CH2:5][N:6]([CH2:9][CH2:10][NH:11][C:12]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:18])[CH2:7][CH2:8]1.[Na+:61].[O-:57][C:58]([OH:59])=[O:60].[O:62]=[CH:63][N:64]([CH3:65])[CH3:66].[P-:33]([F:34])([F:35])([F:36])([F:37])([F:38])[F:39].[n:40]1([O:41][C:42]([N:43]([CH3:44])[CH3:45])=[N+:46]([CH3:47])[CH3:48])[c:49]2[n:50][cH:51][cH:52][cH:53][c:54]2[n:55][n:56]1>>[NH:1]([CH2:2][CH:3]1[CH2:4][CH2:5][N:6]([CH2:9][CH2:10][NH:11][C:12]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:18])[CH2:7][CH2:8]1)[C:23]([c:22]1[cH:21][c:20]([F:19])[cH:28][c:27]([C:29]([F:30])([F:31])[F:32])[cH:26]1)=[O:24]

Komponenten

11

Edukt 10

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 9886HexafluorophosphateHCID 5192223-Fluoro-5-(trifluoromethyl)benzoic acidHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 57993236Tert-butyl 2-(4-(aminomethyl)piperidin-1-yl)ethylcarbamate

Produkt 1

HCID 57993174Tert-butyl 2-(4-((3-fluoro-5-(trifluoromethyl)benzamido)methyl)piperidin-1-yl)ethylcarbamate

Quellen und Nachweise

ORD-Eintrag
ord-b59dd42659404c4fa885a19c369b1456
Quelldatensatz
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

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