1,3-Oxazol-2(5H)-one → 3-{3,5-Difluoro-4-[4-(5-methylpyridin-2-yl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:24])[c:5]([C:9](=[O:10])[N:11]2[CH2:12][CH2:13][N:14]([c:17]3[n:18][cH:19][c:20]([CH3:23])[cH:21][cH:22]3)[CH2:15][CH2:16]2)[c:6]([F:8])[cH:7]1.[O:25]1[C:26](=[O:30])[N:27]=[CH:28][CH2:29]1>>[c:2]1([N:27]2[C:26](=[O:30])[O:25][CH2:29][CH2:28]2)[cH:3][c:4]([F:24])[c:5]([C:9](=[O:10])[N:11]2[CH2:12][CH2:13][N:14]([c:17]3[n:18][cH:19][c:20]([CH3:23])[cH:21][cH:22]3)[CH2:15][CH2:16]2)[c:6]([F:8])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-5e688bd05aec4f5a9f501ba206ccad1f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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