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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1541412Generated: October 25, 2026

Toluene → 2-Hydroxy-3-methyl-4-oxo-4-(2-phenyl-thiazol-5-yl)-butyric Acid Ethyl Ester

https://huagongshe.com/reaction/1541412

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantEthyl oxoacetateHCID 70211—
ReactantIsopropanolateHCID 3260420—
ReactantNpc316347HCID 3280088—
ReactantChlorotitanium(3+)HCID 5325589—
Reactant1-(2-Phenyl-thiazol-5-yl)-propan-1-oneHCID 9855916—
Product2-Hydroxy-3-methyl-4-oxo-4-(2-phenyl-thiazol-5-yl)-butyric Acid Ethyl EsterHCID 9901587—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-c190de285694479b9e56711b15103155
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)