1-Butanol → 4-[7-Benzenesulfonyl-4-(1H-indol-5-ylamino)-7H-pyrrolo[2,3-d]-pyrimidin-6-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester

HRID 1541479Notes

Reaction equation

HRID 1541479 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([c:14]2[cH:15][c:16]3[c:17]([n:18][cH:19][n:20][c:21]3[Cl:22])[n:23]2[S:24](=[O:25])(=[O:26])[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)=[CH:12][CH2:13]1.[CH2:43]([OH:44])[CH2:45][CH2:46][CH3:47].[NH2:33][c:34]1[cH:35][c:36]2[cH:37][cH:38][nH:39][c:40]2[cH:41][cH:42]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([c:14]2[cH:15][c:16]3[c:17]([n:18][cH:19][n:20][c:21]3[NH:33][c:34]3[cH:35][c:36]4[cH:37][cH:38][nH:39][c:40]4[cH:41][cH:42]3)[n:23]2[S:24](=[O:25])(=[O:26])[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)=[CH:12][CH2:13]1

Participants

4

Reactant 3

HCID 2631-ButanolHCID 788675-AminoindoleHCID 58709981tert-butyl 4-(4-chloro-7-(phenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-5,6-dihydropyridine-1(2H)-carboxylate

Product 1

HCID 587099434-[7-Benzenesulfonyl-4-(1H-indol-5-ylamino)-7H-pyrrolo[2,3-d]-pyrimidin-6-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-edda5677179841c89da76605a1e9d93e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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