2-[[2-[1-[2-(2,6-Dimethylmorpholin-4-yl)-2-oxoethyl]-5-oxo-6-phenylmethoxyimidazo[1,2-a]pyrimidin-7-yl]-1,3-thiazol-5-yl]methyl]-5-fluorobenzamide → 2-[[2-[1-[2-(2,6-Dimethylmorpholin-4-yl)-2-oxoethyl]-6-hydroxy-5-oxoimidazo[1,2-a]pyrimidin-7-yl]-1,3-thiazol-5-yl]methyl]-5-fluorobenzamide
Reaction equation
[CH2:19]([c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[O:26][c:27]1[c:28](-[c:48]2[s:49][c:50]([CH2:53][c:54]3[c:55]([C:56](=[O:57])[NH2:58])[cH:59][c:60]([F:63])[cH:61][cH:62]3)[cH:51][n:52]2)[n:29][c:30]2[n:31]([c:32]1=[O:33])[cH:34][cH:35][n:36]2[CH2:37][C:38](=[O:39])[N:40]1[CH2:41][CH:42]([CH3:47])[O:43][CH:44]([CH3:46])[CH2:45]1.[CH3:1][O:2][C:3]([c:4]1[n:5][c:6]2[nH:7][cH:8][cH:9][n:10]2[c:11](=[O:12])[c:13]1[O:14][C:15](=[O:16])[CH3:17])=[O:18]>>[OH:26][c:27]1[c:28](-[c:48]2[s:49][c:50]([CH2:53][c:54]3[c:55]([C:56](=[O:57])[NH2:58])[cH:59][c:60]([F:63])[cH:61][cH:62]3)[cH:51][n:52]2)[n:29][c:30]2[n:31]([c:32]1=[O:33])[cH:34][cH:35][n:36]2[CH2:37][C:38](=[O:39])[N:40]1[CH2:41][CH:42]([CH3:47])[O:43][CH:44]([CH3:46])[CH2:45]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-96fbd9d49ee94880b2318f582aa1d628
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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