4-Hydroxypyrrolidine → {3-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-5-[4-(trifluoromethyl)phenyl]piperidin-1-yl}(3-hydroxy-pyrrolidin-1-yl)methanone

HRID 1541658Notes

Reaction equation

HRID 1541658 reaction equation
[CH:1]1([c:4]2[n:5][o:6][c:7]([CH:9]3[CH2:10][N:11]([C:25](=[O:26])[O:27][c:28]4[cH:29][cH:30][c:31]([N+:32]([O-:33])=[O:34])[cH:35][cH:36]4)[CH2:12][CH:13]([c:15]4[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]4)[CH2:14]3)[n:8]2)[CH2:2][CH2:3]1.[NH:37]1[CH2:38][CH:39]([OH:42])[CH2:40][CH2:41]1>>[CH:1]1([c:4]2[n:5][o:6][c:7]([CH:9]3[CH2:10][N:11]([C:25](=[O:26])[N:37]4[CH2:38][CH:39]([OH:42])[CH2:40][CH2:41]4)[CH2:12][CH:13]([c:15]4[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]4)[CH2:14]3)[n:8]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 982104-HydroxypyrrolidineHCID 580021744-Nitrophenyl 3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-5-[4-(trifluoromethyl)phenyl]piperidine-1-carboxylate

Product 1

HCID 58002523{3-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-5-[4-(trifluoromethyl)phenyl]piperidin-1-yl}(3-hydroxy-pyrrolidin-1-yl)methanone

Sources & evidence

ORD record
ord-6ab2f19c029e4ed88dc509c7e7346ead
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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