2-Amino-5-bromopyridine → 5-[5-(3-Ethoxy-4-trifluoromethyl-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-pyridin-2-ylamine
Reaction equation
[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6](-[c:14]2[n:15][c:16]3[n:17]([c:18]([C:20]([F:21])([F:22])[F:23])[cH:19]2)[n:24][cH:25][c:26]3[C:27]#[CH:28])[cH:7][cH:8][c:9]1[C:10]([F:11])([F:12])[F:13].[NH2:29][c:30]1[n:31][cH:32][c:33]([Br:36])[cH:34][cH:35]1>>[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6](-[c:14]2[n:15][c:16]3[n:17]([c:18]([C:20]([F:21])([F:22])[F:23])[cH:19]2)[n:24][cH:25][c:26]3[C:27]#[C:28][c:33]2[cH:32][n:31][c:30]([NH2:29])[cH:35][cH:34]2)[cH:7][cH:8][c:9]1[C:10]([F:11])([F:12])[F:13]Participants
3
Sources & evidence
- ORD record
- ord-2aad6d385a75491d97b3b405d6bfcd18
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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