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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1542297Generated: October 30, 2026

1,3-Difluorobenzene → 1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-[(5-isopropyl-2,5-diazabicyclo[2.2.1]hept-2-yl)methyl]-3-(4-methoxybenzyl)-3,4-dihydroquinazolin-2(1H)-one

https://huagongshe.com/reaction/1542297

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-DifluorobenzeneHCID 9741—
ReactantBoronic AcidHCID 61668—
Reactant5-bromo-1-(2,6-dichlorophenyl)-7-[(5-isopropyl-2,5-diazabicyclo[2.2.1]hept-2-yl)methyl]-3-(4-methoxybenzyl)-3,4-dihydroquinazolin-2(1H)-oneHCID 22648185—
Product1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-[(5-isopropyl-2,5-diazabicyclo[2.2.1]hept-2-yl)methyl]-3-(4-methoxybenzyl)-3,4-dihydroquinazolin-2(1H)-oneHCID 22647933—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-e78b6cdb8efb4e1ebcfa57736cbe1b07
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)