Dichloromethane → (5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-(2-fluoro-3-hydroxy-phenyl)-methanone

HRID 1542393Notes

Reaction equation

HRID 1542393 reaction equation
[B:22]([Br:23])([Br:24])[Br:25].[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[C:11](=[O:12])[c:13]1[c:14]([F:21])[c:15]([O:19][CH3:20])[cH:16][cH:17][cH:18]1.[CH2:26]([Cl:27])[Cl:28]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[C:11](=[O:12])[c:13]1[c:14]([F:21])[c:15]([OH:19])[cH:16][cH:17][cH:18]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 25134Boron tribromideHCID 57595715(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-(2-fluoro-3-methoxy-phenyl)-methanone

Product 1

HCID 58086399(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-(2-fluoro-3-hydroxy-phenyl)-methanone

Sources & evidence

ORD record
ord-2cda645270264ef2b7451c87274c4149
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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