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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1542443Generated: October 25, 2026

Tetrahydrofuran → 6-chloro-4-(4-bromophenyl)-4-hydroxy-3-(2,2,2-trifluoroethyl)-3,4-dihydroquinazolin-2(1H)-one

https://huagongshe.com/reaction/1542443

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantEthanamine, 2,2,2-trifluoro-HCID 9773—
ReactantN-[4-chloro-2-(4-bromobenzoyl)phenyl]-1H-imidazole-1-carboxamideHCID 59346584—
Product6-chloro-4-(4-bromophenyl)-4-hydroxy-3-(2,2,2-trifluoroethyl)-3,4-dihydroquinazolin-2(1H)-oneHCID 59346596—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-bc9661bd1b1947248829e30ec53a5cce
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)