1-(Cyclopropanesulfonyl)-4-fluorobenzene → 4-(4-Cyclopropanesulfonyl-phenoxy)-2-hydroxymethyl-2-methyl-2,3-dihydro-benzofuran-6-carboxylic acid tert-butyl ester
Reaction equation
[C:26]([CH3:27])([CH3:28])([CH3:29])[O:30][C:31](=[O:32])[c:33]1[cH:34][c:35]2[c:36]([c:43]([OH:45])[cH:44]1)[CH2:37][C:38]([CH3:40])([CH2:41][OH:42])[O:39]2.[CH3:1][O:2][C:3]([c:4]1[cH:5][c:6]([O:7][c:8]2[cH:9][cH:10][c:11]([S:12]([CH3:13])(=[O:14])=[O:15])[cH:16][cH:17]2)[cH:18][c:19]2[c:24]1[CH2:23][CH:21]([CH3:22])[O:20]2)=[O:25].[CH:46]1([S:49](=[O:50])(=[O:51])[c:52]2[cH:53][cH:54][c:55]([F:58])[cH:56][cH:57]2)[CH2:47][CH2:48]1>>[C:26]([CH3:27])([CH3:28])([CH3:29])[O:30][C:31](=[O:32])[c:33]1[cH:34][c:35]2[c:36]([c:43]([O:45][c:55]3[cH:54][cH:53][c:52]([S:49]([CH:46]4[CH2:47][CH2:48]4)(=[O:50])=[O:51])[cH:57][cH:56]3)[cH:44]1)[CH2:37][C:38]([CH3:40])([CH2:41][OH:42])[O:39]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-581c8f96b8994f92a8399627f24c533a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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