Isopropylamine → N-Cyclopropyl-4-methyl-3-[3-[[1-[2-[2-[(1-methylethyl)amino]ethoxy]phenyl]cyclobutyl]amino]-2-oxo-1(2H)-pyrazinyl]-benzamide

HRID 1542500Notes

Reaction equation

HRID 1542500 reaction equation
[CH3:36][CH:37]([CH3:38])[NH2:39].[Cl:1][CH2:2][CH2:3][O:4][c:5]1[c:6]([C:11]2([NH:15][c:16]3[c:17](=[O:35])[n:18](-[c:22]4[cH:23][c:24]([C:25](=[O:26])[NH:27][CH:28]5[CH2:29][CH2:30]5)[cH:31][cH:32][c:33]4[CH3:34])[cH:19][cH:20][n:21]3)[CH2:12][CH2:13][CH2:14]2)[cH:7][cH:8][cH:9][cH:10]1>>[CH2:2]([CH2:3][O:4][c:5]1[c:6]([C:11]2([NH:15][c:16]3[c:17](=[O:35])[n:18](-[c:22]4[cH:23][c:24]([C:25](=[O:26])[NH:27][CH:28]5[CH2:29][CH2:30]5)[cH:31][cH:32][c:33]4[CH3:34])[cH:19][cH:20][n:21]3)[CH2:12][CH2:13][CH2:14]2)[cH:7][cH:8][cH:9][cH:10]1)[NH:39][CH:37]([CH3:36])[CH3:38]

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 666888223-(3-(1-(2-(2-Chloroethoxy)phenyl)cyclobutylamino)-2-oxopyrazin-1(2H)-yl)-N-cyclopropyl-4-methylbenzamide

Product 1

HCID 66689194N-Cyclopropyl-4-methyl-3-[3-[[1-[2-[2-[(1-methylethyl)amino]ethoxy]phenyl]cyclobutyl]amino]-2-oxo-1(2H)-pyrazinyl]-benzamide

Sources & evidence

ORD record
ord-283f9f6f052641f3be860118036182d1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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