(2-Iodo-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone → [5-Methanesulfonyl-2-(4-methyl-imidazol-1-yl)-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone

HRID 1542885Notes

Reaction equation

HRID 1542885 reaction equation
[CH3:30][c:31]1[n:32][cH:33][nH:34][cH:35]1.[I:1][c:2]1[c:3]([C:12](=[O:13])[N:14]2[CH2:15][CH2:16][N:17]([c:20]3[cH:21][cH:22][c:23]([C:26]([F:27])([F:28])[F:29])[cH:24][cH:25]3)[CH2:18][CH2:19]2)[cH:4][c:5]([S:8](=[O:9])(=[O:10])[CH3:11])[cH:6][cH:7]1>>[c:2]1(-[n:34]2[cH:33][n:32][c:31]([CH3:30])[cH:35]2)[c:3]([C:12](=[O:13])[N:14]2[CH2:15][CH2:16][N:17]([c:20]3[cH:21][cH:22][c:23]([C:26]([F:27])([F:28])[F:29])[cH:24][cH:25]3)[CH2:18][CH2:19]2)[cH:4][c:5]([S:8](=[O:9])(=[O:10])[CH3:11])[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 59793691(2-Iodo-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanoneHCID 178418800HCID 178418800, compound

Product 1

HCID 68843179[5-Methanesulfonyl-2-(4-methyl-imidazol-1-yl)-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone

Sources & evidence

ORD record
ord-bd3f81eea68a42dbbb0dd0b5aa62d006
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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