4-Bromobenzenesulfonamide → 4-[5-(4-Chloro-phenyl)-7-cyclopropyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-benzenesulfonamide

HRID 1543033Notes

Reaction equation

HRID 1543033 reaction equation
[Br:22][c:23]1[cH:24][cH:25][c:26]([S:29](=[O:30])(=[O:31])[NH2:32])[cH:27][cH:28]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH:14]4[CH2:15][CH2:16]4)[cH:13]2)[n:17][cH:18][c:19]3[C:20]#[CH:21])[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH:14]4[CH2:15][CH2:16]4)[cH:13]2)[n:17][cH:18][c:19]3[C:20]#[C:21][c:23]2[cH:24][cH:25][c:26]([S:29](=[O:30])(=[O:31])[NH2:32])[cH:27][cH:28]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 696964-BromobenzenesulfonamideHCID 866079965-(4-Chloro-phenyl)-7-cyclopropyl-3-ethynyl-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 118517134-[5-(4-Chloro-phenyl)-7-cyclopropyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-benzenesulfonamide

Sources & evidence

ORD record
ord-0f9a1a37708c4bd09f6a97ebdab4f47c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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