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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 154312Generated: October 26, 2026

1,2-Dimethoxyethane → 5-[(2-Fluorophenyl)ethynyl]-4-methyl-1,3-thiazole

https://huagongshe.com/reaction/154312

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant1-Ethynyl-2-fluorobenzeneHCID 643358—
Reactant5-Bromo-4-methyl-1,3-thiazoleHCID 15020997—
Product5-[(2-Fluorophenyl)ethynyl]-4-methyl-1,3-thiazoleHCID 22291324—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-5a38eb9ca3e048d1b0d8b52df38c558d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)