Ethanol → N-Methyl-N-(piperidin-4-yl)propionamide

HRID 1543206Notes

Reaction equation

HRID 1543206 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([C:15]([CH2:16][CH3:17])=[O:18])[CH3:19])[CH2:12][CH2:13]1.[CH3:20][CH2:21][OH:22].[OH-:23].[OH-:25].[Pd+2:24]>>[NH:8]1[CH2:9][CH2:10][CH:11]([N:14]([C:15]([CH2:16][CH3:17])=[O:18])[CH3:19])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 702EthanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 19761195N-(1-benzylpiperid-4-yl)-N-methylpropionamide

Product 1

HCID 19761222N-Methyl-N-(piperidin-4-yl)propionamide

Sources & evidence

ORD record
ord-1e7678c6981e4c3cb9d592799281d46c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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