HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl Thioglycolate → 5-Trifluoromethyl-benzo[b]thiophene-2-carboxylic acid methyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl Thioglycolate | HCID 16907 | — |
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | 2-Fluoro-5-(trifluoromethyl)benzaldehyde | HCID 2734904 | — |
| Produkt | 5-Trifluoromethyl-benzo[b]thiophene-2-carboxylic acid methyl ester | HCID 1477956 | — |
Reaktionsschritte
Using 4.28 g (22.3 mmol) of 2-fluoro-5-trifluoromethylbenzaldehyde, 1.34 g (33.4 mmol) of sodium hydride (60% pure) and 2.6 g (24.5 mmol) of methyl mercaptoacetate, 4.93 g (80.0% of theory) of the title compound are obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07732477B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-f07e5d856b974215a49ebcc5c811f2ea |
| Quellennotiz | uspto-grants-2010_06 |