Ammonia → N-(3-{5-(2-Amino-4-pyrimidinyl)-2-[4-(methylsulfonyl)-1-piperazinyl]-1,3-thiazol-4-yl}-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
Reaction equation
[CH3:43][OH:44].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:23]3[c:24]([F:41])[c:25]([NH:29][S:30](=[O:31])(=[O:32])[c:33]4[c:34]([F:40])[cH:35][cH:36][cH:37][c:38]4[F:39])[cH:26][cH:27][cH:28]3)[n:10][c:11]([N:13]3[CH2:14][CH2:15][N:16]([S:19](=[O:20])(=[O:21])[CH3:22])[CH2:17][CH2:18]3)[s:12]2)[n:7]1.[NH3:42]>>[c:2]1([NH2:42])[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:23]3[c:24]([F:41])[c:25]([NH:29][S:30](=[O:31])(=[O:32])[c:33]4[c:34]([F:40])[cH:35][cH:36][cH:37][c:38]4[F:39])[cH:26][cH:27][cH:28]3)[n:10][c:11]([N:13]3[CH2:14][CH2:15][N:16]([S:19](=[O:20])(=[O:21])[CH3:22])[CH2:17][CH2:18]3)[s:12]2)[n:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-863e885046104308acaa5b322c56e492
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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