(Pyridin-4-yl)boronic acid → N-(1H-indol-5-yl)-3-[2-pyridin-4-yl-4-(trifluoromethyl)phenyl]prop-2-enamide

HRID 1543762Notes

Reaction equation

HRID 1543762 reaction equation
[Br:1][c:2]1[c:3]([CH:12]=[CH:13][C:14](=[O:15])[NH:16][c:17]2[cH:18][c:19]3[cH:20][cH:21][nH:22][c:23]3[cH:24][cH:25]2)[cH:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[n:26]1[cH:27][cH:28][c:29]([B:32]([OH:33])[OH:34])[cH:30][cH:31]1>>[c:2]1(-[c:29]2[cH:28][cH:27][n:26][cH:31][cH:30]2)[c:3]([CH:12]=[CH:13][C:14](=[O:15])[NH:16][c:17]2[cH:18][c:19]3[cH:20][cH:21][nH:22][c:23]3[cH:24][cH:25]2)[cH:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1

Participants

3

Reactant 2

HCID 2734379(Pyridin-4-yl)boronic acidHCID 688724933-[2-bromo-4-(trifluoromethyl)phenyl]-N-(1H-indol-5-yl)prop-2-enamide

Product 1

HCID 68874571N-(1H-indol-5-yl)-3-[2-pyridin-4-yl-4-(trifluoromethyl)phenyl]prop-2-enamide

Sources & evidence

ORD record
ord-55403acde0ac41e69431002bd9cd6a48
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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