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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1543777Generated: October 27, 2026

3-Cyano-3-phenylpropanoic acid → 4-[7-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3,4-dihydroisoquinolin-2(1h)-yl]-4-oxo-2-phenylbutanenitrile

https://huagongshe.com/reaction/1543777

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Cyano-3-phenylpropanoic acidHCID 11194625—
Reactantpiperidin-4-yl 7-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3,4-dihydroisoquinoline-2(1H)-carboxylateHCID 59496558—
Product4-[7-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3,4-dihydroisoquinolin-2(1h)-yl]-4-oxo-2-phenylbutanenitrileHCID 59496697—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-9b773d1c019d44adaa83a599a49c5b24
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)