(6-Fluoropyridin-3-yl)boronic acid → 10-(6-fluoropyridin-3-yl)-2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine

HRID 1543949Notes

Reaction equation

HRID 1543949 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:24]1)-[c:7]1[n:8]([cH:12][c:13](-[c:15]3[n:16][c:17]([CH3:23])[n:18][n:19]3[CH:20]([CH3:21])[CH3:22])[n:14]1)[CH2:9][CH2:10][O:11]2.[F:25][c:26]1[cH:27][cH:28][c:29]([B:32]([OH:33])[OH:34])[cH:30][n:31]1>>[c:2]1(-[c:29]2[cH:28][cH:27][c:26]([F:25])[n:31][cH:30]2)[cH:3][cH:4][c:5]2[c:6]([cH:24]1)-[c:7]1[n:8]([cH:12][c:13](-[c:15]3[n:16][c:17]([CH3:23])[n:18][n:19]3[CH:20]([CH3:21])[CH3:22])[n:14]1)[CH2:9][CH2:10][O:11]2

Participants

3

Reactant 2

HCID 2783397(6-Fluoropyridin-3-yl)boronic acidHCID 5820476010-bromo-2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine

Product 1

HCID 5820452110-(6-fluoropyridin-3-yl)-2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine

Sources & evidence

ORD record
ord-2adfdc9f2c5a47adb6179e6feb9faec1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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