1,2-Dimethoxyethane → 5-[2-(4-Chloro-phenyl)-2H-pyrazol-3-yl]-6-methyl-2-oxo-1-(3-trifluoromethyl-phenyl)-1,2-dihydro-pyridine-3-carboxylic Acid Methylamide

HRID 1544096Notes

Reaction equation

HRID 1544096 reaction equation
[CH3:26][NH:27][C:28](=[O:29])[c:30]1[c:31](=[O:48])[n:32](-[c:38]2[cH:39][c:40]([C:44]([F:45])([F:46])[F:47])[cH:41][cH:42][cH:43]2)[c:33]([CH3:37])[c:34]([I:36])[cH:35]1.[CH3:49][O:50][CH2:51][CH2:52][O:53][CH3:54].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][cH:11][c:12]2[Sn:13]([CH2:14][CH2:15][CH2:16][CH3:17])([CH2:18][CH2:19][CH2:20][CH3:21])[CH2:22][CH2:23][CH2:24][CH3:25])[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][cH:11][c:12]2-[c:34]2[c:33]([CH3:37])[n:32](-[c:38]3[cH:39][c:40]([C:44]([F:45])([F:46])[F:47])[cH:41][cH:42][cH:43]3)[c:31](=[O:48])[c:30]([C:28]([NH:27][CH3:26])=[O:29])[cH:35]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 80711,2-DimethoxyethaneHCID 673427675-iodo-N,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamideHCID 673457041-(4-chlorophenyl)-5-tributylstannyl-1H-pyrazole

Product 1

HCID 248306675-[2-(4-Chloro-phenyl)-2H-pyrazol-3-yl]-6-methyl-2-oxo-1-(3-trifluoromethyl-phenyl)-1,2-dihydro-pyridine-3-carboxylic Acid Methylamide

Sources & evidence

ORD record
ord-21f1c27554d74bedbfe19ddb3a675eaa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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