4-(Trifluoromethyl)thiazole-2-carboxylic acid → N-(6-acetyl-2-chloro-3-methoxyphenyl)-4-trifluoromethylthiazole-2-carboxamide
Reaction equation
[C:26]([c:27]1[c:28]([NH:29][C:30]([C:31]2=[N:39][CH:34]([C:35]([F:36])([F:37])[F:38])[CH2:33][S:32]2)=[O:40])[c:41]([CH3:42])[c:43]([O:44][CH3:45])[cH:46][cH:47]1)(=[O:48])[CH3:49].[F:1][C:2]([c:3]1[n:4][c:5]([C:8](=[O:9])[OH:10])[s:6][cH:7]1)([F:11])[F:12].[NH2:13][c:14]1[c:15]([C:23]([CH3:24])=[O:25])[cH:16][cH:17][c:18]([O:21][CH3:22])[c:19]1[Cl:20]>>[F:1][C:2]([c:3]1[n:4][c:5]([C:8](=[O:10])[NH:13][c:14]2[c:15]([C:23]([CH3:24])=[O:25])[cH:16][cH:17][c:18]([O:21][CH3:22])[c:19]2[Cl:20])[s:6][cH:7]1)([F:11])[F:12]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-b64ff4c7175b474d9ee59f1de386b097
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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