Water → 2-(4-((2,6-Dimethoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)quinolin-8-yl)amino)pentyl)isoindoline-1,3-dione
Reaction equation
[CH3:52][C:53]#[N:54].[CH:28]([NH:29][CH:30]([CH3:31])[CH3:32])([CH3:33])[CH3:34].[I:35][CH:36]([CH2:37][CH2:38][CH2:39][N:40]1[C:41](=[O:50])[c:42]2[c:43]([cH:46][cH:47][cH:48][cH:49]2)[C:44]1=[O:45])[CH3:51].[NH2:1][c:2]1[cH:3][c:4]([O:26][CH3:27])[c:5]([O:15][c:16]2[cH:17][c:18]([C:22]([F:23])([F:24])[F:25])[cH:19][cH:20][cH:21]2)[c:6]2[c:7]([CH3:14])[cH:8][c:9]([O:12][CH3:13])[n:10][c:11]12.[OH2:55]>>[NH:1]([c:2]1[cH:3][c:4]([O:26][CH3:27])[c:5]([O:15][c:16]2[cH:17][c:18]([C:22]([F:23])([F:24])[F:25])[cH:19][cH:20][cH:21]2)[c:6]2[c:7]([CH3:14])[cH:8][c:9]([O:12][CH3:13])[n:10][c:11]12)[CH:36]([CH2:37][CH2:38][CH2:39][N:40]1[C:41](=[O:50])[c:42]2[c:43]([cH:46][cH:47][cH:48][cH:49]2)[C:44]1=[O:45])[CH3:51]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f275c21f779f49bd8414c80b814857ca
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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