4-Chloro-2-toluidine → 2-(2-Methyl-4-chloro-phenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid cyclobutylmethyl-amide

HRID 1544706Notes

Reaction equation

HRID 1544706 reaction equation
[CH3:20][c:21]1[c:22]([NH2:23])[cH:24][cH:25][c:26]([Cl:28])[cH:27]1.[CH:1]1([CH2:5][NH:6][C:7](=[O:8])[c:9]2[c:10]([C:16]([F:17])([F:18])[F:19])[n:11][c:12]([Cl:15])[n:13][cH:14]2)[CH2:2][CH2:3][CH2:4]1.[O:29]1[CH2:30][CH2:31][O:32][CH2:33][CH2:34]1>>[CH:1]1([CH2:5][NH:6][C:7](=[O:8])[c:9]2[c:10]([C:16]([F:17])([F:18])[F:19])[n:11][c:12]([NH:23][c:22]3[c:21]([CH3:20])[cH:27][c:26]([Cl:28])[cH:25][cH:24]3)[n:13][cH:14]2)[CH2:2][CH2:3][CH2:4]1

Participants

4

Reactant 3

HCID 72514-Chloro-2-toluidineHCID 312751,4-DioxaneHCID 579826652-Chloro-4-trifluoromethyl-pyrimidin-5-carboxylic acid cyclobutylmethyl-amide

Product 1

HCID 579825792-(2-Methyl-4-chloro-phenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid cyclobutylmethyl-amide

Sources & evidence

ORD record
ord-3dc47298ec4d4dbab3c90683216dac17
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…