4-Amino-1-Boc-piperidine → 1,1-Dimethylethyl 4-[(3-cyano-4-fluorophenyl)amino]-1-piperidinecarboxylate

HRID 1544806Notes

Reaction equation

HRID 1544806 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([F:10])[c:6]([C:7]#[N:8])[cH:9]1.[NH2:11][CH:12]1[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]1>>[c:2]1([NH:11][CH:12]2[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]2)[cH:3][cH:4][c:5]([F:10])[c:6]([C:7]#[N:8])[cH:9]1

Participants

3

Reactant 2

HCID 12682914-Amino-1-Boc-piperidineHCID 27249005-Bromo-2-fluorobenzonitrile

Product 1

HCID 671280881,1-Dimethylethyl 4-[(3-cyano-4-fluorophenyl)amino]-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-98a7b7e2aa1c40e8995d06843c12e8b8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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