2-Amino-5-(2-fluorophenyl)thiophene-3-carboxamide → 2-{[6-(1,2-Dihydroxyethyl)pyridin-2-yl]amino}-5-(2-fluorophenyl)thiophene-3-carboxamide
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([CH:8]([CH2:9][OH:10])[OH:11])[n:7]1.[NH2:12][c:13]1[s:14][c:15](-[c:21]2[c:22]([F:27])[cH:23][cH:24][cH:25][cH:26]2)[cH:16][c:17]1[C:18](=[O:19])[NH2:20]>>[c:2]1([NH:12][c:13]2[s:14][c:15](-[c:21]3[c:22]([F:27])[cH:23][cH:24][cH:25][cH:26]3)[cH:16][c:17]2[C:18](=[O:19])[NH2:20])[cH:3][cH:4][cH:5][c:6]([CH:8]([CH2:9][OH:10])[OH:11])[n:7]1Participants
3
Sources & evidence
- ORD record
- ord-9c416f8f0d504767a4421b46a7c4a8d0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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