2-Fluoroethyl bromide → 5-(2-Fluoroethoxy)pyridine-2-carboxylic acid

HRID 1544944Notes

Reaction equation

HRID 1544944 reaction equation
[Br:26][CH2:27][CH2:28][F:29].[CH3:15][O:16][C:17]([c:18]1[cH:19][cH:20][c:21]([OH:22])[cH:23][n:24]1)=[O:25].[CH3:30][O:31][C:32](=[O:33])[c:34]1[n:35][cH:36][c:37]([O:40][CH2:41][CH2:42][F:43])[cH:38][cH:39]1.[CH:1]1([CH2:2][O:3][c:4]2[cH:5][cH:6][c:7]([C:8]([OH:9])=[O:10])[n:11][cH:12]2)[CH2:13][CH2:14]1>>[O:31]=[C:32]([OH:33])[c:34]1[n:35][cH:36][c:37]([O:40][CH2:41][CH2:42][F:43])[cH:38][cH:39]1

Participants

5

Reactant 4

HCID 129822-Fluoroethyl bromideHCID 4715126Methyl 5-hydroxypyridine-2-carboxylateHCID 666918955-(Cyclopropylmethoxy)pyridine-2-carboxylic acidHCID 866512285-(2-Fluoro-ethoxy)-pyridine-2-carboxylic acid methyl ester

Product 1

HCID 790070915-(2-Fluoroethoxy)pyridine-2-carboxylic acid

Sources & evidence

ORD record
ord-34d14b4d26e54a2b9e498b5a82243255
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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