Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 154532Generated: October 26, 2026

Tetrahydrofuran → Methyl 2-(2-fluorophenylamino)-3,4-difluoro-5-((trimethylsilyl)ethynyl)benzoate

https://huagongshe.com/reaction/154532

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantTrimethylsilylacetyleneHCID 66111—
ReactantMethyl 5-bromo-2-(2-fluorophenylamino)-3,4-difluorobenzoateHCID 59519391—
ProductMethyl 2-(2-fluorophenylamino)-3,4-difluoro-5-((trimethylsilyl)ethynyl)benzoateHCID 59519400—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-e9dd497c58a34eb898644fc6331286e7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)