Methanol → tert-Butyl 4-(aminomethyl)-4-(4-cyclopropylpiperazin-1-yl)-piperidine-1-carboxylate

HRID 1545322Notes

Reaction equation

HRID 1545322 reaction equation
[CH3:33][OH:34].[CH:1]1([N:4]2[CH2:5][CH2:6][N:7]([C:10]3([CH2:23][NH:24][C:25](=[O:26])[C:27]([F:28])([F:29])[F:30])[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]3)[CH2:8][CH2:9]2)[CH2:2][CH2:3]1.[Na+:32].[OH-:31]>>[CH:1]1([N:4]2[CH2:5][CH2:6][N:7]([C:10]3([CH2:23][NH2:24])[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]3)[CH2:8][CH2:9]2)[CH2:2][CH2:3]1

Participants

5

Reactant 4

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 57989615HCID 57989615, compound

Product 1

HCID 57989604tert-Butyl 4-(aminomethyl)-4-(4-cyclopropylpiperazin-1-yl)-piperidine-1-carboxylate

Sources & evidence

ORD record
ord-f227e58d99654f9680bbe10aa747c37d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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