HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1545474Generated: October 25, 2026
Acetic Acid → 3-(5-Chloro-3-fluoropyridin-2-yl)-2-methyl-3-oxopropionic acid tert-butyl ester
https://huagongshe.com/reaction/1545474
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Diisopropylamine | HCID 7912 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Hexane | HCID 8058 | — |
| Reactant | tert-Butyl methyl ether | HCID 15413 | — |
| Reactant | tert-Butyl propionate | HCID 88561 | — |
| Reactant | Ethyl 5-chloro-3-fluoropicolinate | HCID 22013569 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | 3-(5-Chloro-3-fluoropyridin-2-yl)-2-methyl-3-oxopropionic acid tert-butyl ester | HCID 22013577 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (1/10) |
|---|
| ORD ID | ord-4c8639124b8a4d84a4fed30f684d8aba |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (1/10) |
|---|
