3-(4-Bromophenyl)-5-({[tert-butyl(dimethyl)silyl]oxy}methyl)-4,5-dihydroisoxazole → N-[[3-[4-[4-[5-[[tert-butyl(dimethyl)silyl]oxymethyl]-4,5-dihydro-1,2-oxazol-3-yl]phenyl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

HRID 1545496Notes

Reaction equation

HRID 1545496 reaction equation
[Br:22][c:23]1[cH:24][cH:25][c:26]([C:29]2=[N:30][O:31][CH:32]([CH2:34][O:35][Si:36]([CH3:37])([CH3:38])[C:39]([CH3:40])([CH3:41])[CH3:42])[CH2:33]2)[cH:27][cH:28]1.[O:1]=[C:2]1[O:3][CH:4]([CH2:17][NH:18][C:19]([CH3:20])=[O:21])[CH2:5][N:6]1[c:7]1[cH:8][cH:9][c:10]([Sn:13]([CH3:14])([CH3:15])[CH3:16])[cH:11][cH:12]1>>[O:1]=[C:2]1[O:3][CH:4]([CH2:17][NH:18][C:19]([CH3:20])=[O:21])[CH2:5][N:6]1[c:7]1[cH:8][cH:9][c:10](-[c:23]2[cH:24][cH:25][c:26]([C:29]3=[N:30][O:31][CH:32]([CH2:34][O:35][Si:36]([CH3:37])([CH3:38])[C:39]([CH3:40])([CH3:41])[CH3:42])[CH2:33]3)[cH:27][cH:28]2)[cH:11][cH:12]1

Participants

3

Reactant 2

HCID 179544873-(4-Bromophenyl)-5-({[tert-butyl(dimethyl)silyl]oxy}methyl)-4,5-dihydroisoxazoleHCID 22479436N-[[2-oxo-3-(4-trimethylstannylphenyl)-1,3-oxazolidin-5-yl]methyl]acetamide

Product 1

HCID 69255725N-[[3-[4-[4-[5-[[tert-butyl(dimethyl)silyl]oxymethyl]-4,5-dihydro-1,2-oxazol-3-yl]phenyl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

Sources & evidence

ORD record
ord-6037b70952e848ef9dfb3b44e6582dd1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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