3-(5-chloro-4-fluoro-2-hydroxyphenyl)-3-hydroxy-1-pentyl-1,3-dihydro-2H-indol-2-one → 3-(5-chloro-4-fluoro-2-hydroxyphenyl)-1-pentyl-1,3-dihydro-2H-indol-2-one

HRID 1545521Notes

Reaction equation

HRID 1545521 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([OH:6])[c:7]([C:8]2([OH:9])[c:10]3[c:11]([cH:12][cH:13][cH:14][cH:15]3)[N:16]([CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[C:22]2=[O:23])[cH:24]1.[Cl:25][c:26]1[c:27]([F:49])[cH:28][c:29]([OH:48])[c:30]([C:32]2([OH:47])[C:33](=[O:46])[N:34]([CH2:41][CH2:42][CH2:43][CH2:44][CH3:45])[c:35]3[cH:36][cH:37][cH:38][cH:39][c:40]32)[cH:31]1>>[Cl:25][c:26]1[c:27]([F:49])[cH:28][c:29]([OH:48])[c:30]([CH:32]2[C:33](=[O:46])[N:34]([CH2:41][CH2:42][CH2:43][CH2:44][CH3:45])[c:35]3[cH:36][cH:37][cH:38][cH:39][c:40]32)[cH:31]1

Participants

3

Reactant 2

HCID 120043063-(5-chloro-4-fluoro-2-hydroxyphenyl)-3-hydroxy-1-pentyl-1,3-dihydro-2H-indol-2-oneHCID 588724783-(5-bromo-2-hydroxyphenyl)-3-hydroxy-1-pentyl-1,3-dihydro-2H-indol-2-one

Product 1

HCID 588724353-(5-chloro-4-fluoro-2-hydroxyphenyl)-1-pentyl-1,3-dihydro-2H-indol-2-one

Sources & evidence

ORD record
ord-1dd3ba87231f47dca4c499ee95a924ed
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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