(4-Fluoro-2-methoxyphenyl)boronic acid → 4-amino-7-fluoro-8-(4-fluoro-2-methoxy-phenyl)-N-propyl-cinnoline-3-carboxamide
Reaction equation
[CH3:20][O:21][c:22]1[c:23]([B:29]([OH:30])[OH:31])[cH:24][cH:25][c:26]([F:28])[cH:27]1.[NH2:1][c:2]1[c:3]([C:14](=[O:15])[NH:16][CH2:17][CH2:18][CH3:19])[n:4][n:5][c:6]2[c:7]([I:13])[c:8]([F:12])[cH:9][cH:10][c:11]12>>[NH2:1][c:2]1[c:3]([C:14](=[O:15])[NH:16][CH2:17][CH2:18][CH3:19])[n:4][n:5][c:6]2[c:7](-[c:23]3[c:22]([O:21][CH3:20])[cH:27][c:26]([F:28])[cH:25][cH:24]3)[c:8]([F:12])[cH:9][cH:10][c:11]12Participants
3
Sources & evidence
- ORD record
- ord-800fd67c9b5146719999dae60d9c8b6f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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