2-(3-Acetyl-phenoxy)-nicotinic acid → 2-(3-Acetyl-phenoxy)-N-(2-fluoro-4-(1-hydroxy-1-methyl-ethyl)-benzyl)-nicotinamide

HRID 1545614Notes

Reaction equation

HRID 1545614 reaction equation
[C:1]([CH3:2])(=[O:3])[c:4]1[cH:5][c:6]([O:7][c:8]2[c:9]([C:10](=[O:11])[OH:12])[cH:13][cH:14][cH:15][n:16]2)[cH:17][cH:18][cH:19]1.[NH2:20][CH2:21][c:22]1[c:23]([F:32])[cH:24][c:25]([C:28]([CH3:29])([CH3:30])[OH:31])[cH:26][cH:27]1>>[C:1]([CH3:2])(=[O:3])[c:4]1[cH:5][c:6]([O:7][c:8]2[c:9]([C:10](=[O:12])[NH:20][CH2:21][c:22]3[c:23]([F:32])[cH:24][c:25]([C:28]([CH3:29])([CH3:30])[OH:31])[cH:26][cH:27]3)[cH:13][cH:14][cH:15][n:16]2)[cH:17][cH:18][cH:19]1

Participants

3

Reactant 2

HCID 122026462-(3-Acetyl-phenoxy)-nicotinic acidHCID 224816482-(4-Aminomethyl-3-fluoro-phenyl)-propan-2-ol

Product 1

HCID 226122332-(3-Acetyl-phenoxy)-N-(2-fluoro-4-(1-hydroxy-1-methyl-ethyl)-benzyl)-nicotinamide

Sources & evidence

ORD record
ord-2dd9e7d63bfb45f0b05b375d4e99aeec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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