8-[[2-[tert-butyl(dimethyl)silyl]oxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]-N-[[1,6-diethyl-4-(oxan-4-ylamino)pyrazolo[3,4-b]pyridin-5-yl]methyl]octanamide → N-[[1,6-diethyl-4-(oxan-4-ylamino)pyrazolo[3,4-b]pyridin-5-yl]methyl]-8-[[2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]octanamide
Reaction equation
[C:26]([Si:27]([CH3:28])([CH3:29])[O:31][CH:32]([CH2:33][NH:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][C:42](=[O:43])[NH:44][CH2:45][c:46]1[c:47]([NH:59][CH:60]2[CH2:61][CH2:62][O:63][CH2:64][CH2:65]2)[c:48]2[c:49]([n:50][c:51]1[CH2:52][CH3:53])[n:54]([CH2:57][CH3:58])[n:55][cH:56]2)[c:66]1[c:67]2[cH:68][cH:69][c:70](=[O:77])[nH:71][c:72]2[c:73]([OH:76])[cH:74][cH:75]1)([CH3:30])([CH3:78])[CH3:79].[N:1]([CH2:2][CH:3]([c:4]1[cH:5][cH:6][c:7]([O:8][CH2:9][c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[c:16]2[c:17]1[cH:18][cH:19][c:20](=[O:21])[nH:22]2)[OH:23])=[N+:24]=[N-:25]>>[OH:31][CH:32]([CH2:33][NH:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][C:42](=[O:43])[NH:44][CH2:45][c:46]1[c:47]([NH:59][CH:60]2[CH2:61][CH2:62][O:63][CH2:64][CH2:65]2)[c:48]2[c:49]([n:50][c:51]1[CH2:52][CH3:53])[n:54]([CH2:57][CH3:58])[n:55][cH:56]2)[c:66]1[c:67]2[cH:68][cH:69][c:70](=[O:77])[nH:71][c:72]2[c:73]([OH:76])[cH:74][cH:75]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-a5804c9332d346d088711e688729db5f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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