3-Aminophenol → N4-(3-chloro-4-methoxyphenyl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-pyrimidinediamine

HRID 1545745Notes

Reaction equation

HRID 1545745 reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([F:18])[c:6]([NH:8][c:9]2[cH:10][c:11]([Cl:17])[c:12]([O:15][CH3:16])[cH:13][cH:14]2)[n:7]1.[OH:19][c:20]1[cH:21][c:22]([NH2:23])[cH:24][cH:25][cH:26]1>>[c:2]1([NH:23][c:22]2[cH:21][c:20]([OH:19])[cH:26][cH:25][cH:24]2)[n:3][cH:4][c:5]([F:18])[c:6]([NH:8][c:9]2[cH:10][c:11]([Cl:17])[c:12]([O:15][CH3:16])[cH:13][cH:14]2)[n:7]1

Participants

3

Reactant 2

HCID 115683-AminophenolHCID 220611152-chloro-N4-(3-chloro-4-methoxyphenyl)-5-fluoro-4-pyrimidineamine

Product 1

HCID 22060225N4-(3-chloro-4-methoxyphenyl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-a6a164a90e3e4c928cf5cb8dd56a32b0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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