3,4-Difluorobenzylamine → N-(3,4-difluorobenzyl)-2-(2,6-difluorophenyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide

HRID 154611Notes

Reaction equation

HRID 154611 reaction equation
[CH2:1]([O:2][C:4](=[O:5])[c:6]1[n:7][c:8](-[c:15]2[c:16]([F:22])[cH:17][cH:18][cH:19][c:20]2[F:21])[n:9]([CH3:14])[c:10](=[O:13])[c:11]1[OH:12])[CH3:3].[F:23][c:24]1[cH:25][c:26]([CH2:27][NH2:28])[cH:29][cH:30][c:31]1[F:32]>>[C:4](=[O:5])([c:6]1[n:7][c:8](-[c:15]2[c:16]([F:22])[cH:17][cH:18][cH:19][c:20]2[F:21])[n:9]([CH3:14])[c:10](=[O:13])[c:11]1[OH:12])[NH:28][CH2:27][c:26]1[cH:25][c:24]([F:23])[c:31]([F:32])[cH:30][cH:29]1

Participants

3

Reactant 2

HCID 1235723,4-DifluorobenzylamineHCID 546914342-(2,6-Difluoro-phenyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydro-pyrimidine-4-carboxylic acid ethyl ester

Product 1

HCID 54711131N-(3,4-difluorobenzyl)-2-(2,6-difluorophenyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide

Sources & evidence

ORD record
ord-86921ceab02e47c094b4944949da03ec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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