3-[4-(2-Cyclopropyl-3-methyl-3H-imidazol-4-yl)-1,2,3-triazol-1-yl]-N-[5-(2-hydroxy-1,1-dimethyl-ethyl)-3-methanesulfonylamino-2-methoxy-phenyl]-4-methyl-benzamide → N-[5-(2-Hydroxy-1,1-dimethyl-ethyl)-3-methanesulfonylamino-2-methoxy-phenyl]-4-methyl-3-{4-[3-methyl-2-(1-methyl-cyclopropyl)-3H-imidazol-4-yl]-1,2,3-triazol-1-yl}-benzamide

HRID 1546185Notes

Reaction equation

HRID 1546185 reaction equation
[C:43]([c:44]1[n:45]([CH3:46])[c:47]([C:48]2([CH3:49])[CH2:50][CH2:51]2)[n:52][cH:53]1)#[CH:54].[CH:1]1([c:4]2[n:5][cH:6][c:7](-[c:10]3[n:11][n:12][n:13](-[c:15]4[cH:16][c:17]([C:18](=[O:19])[NH:20][c:21]5[c:22]([O:37][CH3:38])[c:23]([NH:32][S:33](=[O:34])(=[O:35])[CH3:36])[cH:24][c:25]([C:27]([CH2:28][OH:29])([CH3:30])[CH3:31])[cH:26]5)[cH:39][cH:40][c:41]4[CH3:42])[cH:14]3)[n:8]2[CH3:9])[CH2:2][CH2:3]1>>[C:1]1([c:4]2[n:5][cH:6][c:7](-[c:10]3[n:11][n:12][n:13](-[c:15]4[cH:16][c:17]([C:18](=[O:19])[NH:20][c:21]5[c:22]([O:37][CH3:38])[c:23]([NH:32][S:33](=[O:34])(=[O:35])[CH3:36])[cH:24][c:25]([C:27]([CH2:28][OH:29])([CH3:30])[CH3:31])[cH:26]5)[cH:39][cH:40][c:41]4[CH3:42])[cH:14]3)[n:8]2[CH3:9])([CH3:43])[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 210970803-[4-(2-Cyclopropyl-3-methyl-3H-imidazol-4-yl)-1,2,3-triazol-1-yl]-N-[5-(2-hydroxy-1,1-dimethyl-ethyl)-3-methanesulfonylamino-2-methoxy-phenyl]-4-methyl-benzamideHCID 210973465-ethynyl-1-methyl-2-(1-methyl-cyclopropyl)-1H-imidazole

Product 1

HCID 21097101N-[5-(2-Hydroxy-1,1-dimethyl-ethyl)-3-methanesulfonylamino-2-methoxy-phenyl]-4-methyl-3-{4-[3-methyl-2-(1-methyl-cyclopropyl)-3H-imidazol-4-yl]-1,2,3-triazol-1-yl}-benzamide

Sources & evidence

ORD record
ord-96d7bab32f35403fbe26ff51188f618f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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