N,N-Dimethylpropargylamine → N-(2-chlorophenyl)-8-(3-(dimethylamino)prop-1-ynyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide

HRID 1546388Notes

Reaction equation

HRID 1546388 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:26]1)[O:7][CH2:8][CH2:9][c:10]1[c:11]-2[s:12][c:13]([C:15](=[O:16])[N:17]([CH3:18])[c:19]2[c:20]([Cl:25])[cH:21][cH:22][cH:23][cH:24]2)[cH:14]1.[CH3:27][N:28]([CH3:29])[CH2:30][C:31]#[CH:32]>>[c:2]1([C:32]#[C:31][CH2:30][N:28]([CH3:27])[CH3:29])[cH:3][cH:4][c:5]2[c:6]([cH:26]1)[O:7][CH2:8][CH2:9][c:10]1[c:11]-2[s:12][c:13]([C:15](=[O:16])[N:17]([CH3:18])[c:19]2[c:20]([Cl:25])[cH:21][cH:22][cH:23][cH:24]2)[cH:14]1

Participants

3

Reactant 2

HCID 81643N,N-DimethylpropargylamineHCID 442424278-bromo-N-(2-chlorophenyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide

Product 1

HCID 44242232N-(2-chlorophenyl)-8-(3-(dimethylamino)prop-1-ynyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide

Sources & evidence

ORD record
ord-f00b0b6acac64a21abf4bb9e17c82202
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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