4-Benzyl-4-piperidinol → (RS)-4-Benzyl-1-(5-benzyloxy-2,3-dihydro-benzofuran-2-ylmethyl)-piperidin-4-ol

HRID 1546653Notes

Reaction equation

HRID 1546653 reaction equation
[CH2:15]([c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1)[O:22][c:23]1[cH:24][cH:25][c:26]2[c:27]([cH:33]1)[CH2:28][CH:29]([CH2:31][Br:32])[O:30]2.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[C:8]1([OH:14])[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[C:8]1([OH:14])[CH2:9][CH2:10][N:11]([CH2:31][CH:29]2[CH2:28][c:27]3[c:26]([cH:25][cH:24][c:23]([O:22][CH2:15][c:16]4[cH:17][cH:18][cH:19][cH:20][cH:21]4)[cH:33]3)[O:30]2)[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 981524-Benzyl-4-piperidinolHCID 22628347(RS)-5-Benzyloxy-2-bromomethyl-2,3-dihydro-benzofuran

Product 1

HCID 22628367(RS)-4-Benzyl-1-(5-benzyloxy-2,3-dihydro-benzofuran-2-ylmethyl)-piperidin-4-ol

Sources & evidence

ORD record
ord-6b799f310e0e42bba28ac0023602639d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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