1-(4-Bromophenyl)-4-methylpiperazine → [8-(2-Methanesulfonyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[4-(4-methyl-piperazin-1-yl)-phenyl]-amine

HRID 1546834Notes

Reaction equation

HRID 1546834 reaction equation
[Br:21][c:22]1[cH:23][cH:24][c:25]([N:28]2[CH2:29][CH2:30][N:31]([CH3:34])[CH2:32][CH2:33]2)[cH:26][cH:27]1.[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[c:6](-[c:11]2[c:12]3[n:13]([cH:14][cH:15][cH:16]2)[n:17][c:18]([NH2:20])[n:19]3)[cH:7][cH:8][cH:9][cH:10]1.[CH:35]1([P:36]([CH:37]2[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42]2)[c:43]2[cH:44][cH:45][cH:46][cH:47][c:48]2-[c:49]2[cH:50][cH:51][cH:52][cH:53][c:54]2[P:55]([CH:56]2[CH2:57][CH2:58][CH2:59][CH2:60][CH2:61]2)[CH:62]2[CH2:63][CH2:64][CH2:65][CH2:66][CH2:67]2)[CH2:68][CH2:69][CH2:70][CH2:71][CH2:72]1>>[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[c:6](-[c:11]2[c:12]3[n:13]([cH:14][cH:15][cH:16]2)[n:17][c:18]([NH:20][c:22]2[cH:23][cH:24][c:25]([N:28]4[CH2:29][CH2:30][N:31]([CH3:34])[CH2:32][CH2:33]4)[cH:26][cH:27]2)[n:19]3)[cH:7][cH:8][cH:9][cH:10]1

Participants

4

Reactant 3

HCID 118176751-(4-Bromophenyl)-4-methylpiperazineHCID 249469872,2'-Bis(dicyclohexylphosphino)-1,1'-biphenylHCID 674815228-(2-Methanesulfonyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine

Product 1

HCID 49839253[8-(2-Methanesulfonyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[4-(4-methyl-piperazin-1-yl)-phenyl]-amine

Sources & evidence

ORD record
ord-dae89d113f0b4a33b6ceab7fbcc7c96c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…