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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1546854Generated: November 2, 2026

Sodium ion → 5-(1,4-Dioxa-spiro[4.5]dec-7-en-8-yl)-3-[(trans-4-hydroxy-cyclohexyl)-(trans-4-methyl-cyclohexane-carbonyl)-amino]-thiophene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/1546854

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantDimethylformamideHCID 6228—
ReactantCarbonate IonHCID 19660—
Reactant1,4-Dioxaspiro[4.5]dec-7-en-8-ylboronic acidHCID 44118765—
Reactant5-Bromo-3-[(4-hydroxy-cyclohexyl)-(4-methyl-cyclohexanecarbonyl)-amino]-thiophene-2-carboxylic acid methyl esterHCID 57795364—
Product5-(1,4-Dioxa-spiro[4.5]dec-7-en-8-yl)-3-[(trans-4-hydroxy-cyclohexyl)-(trans-4-methyl-cyclohexane-carbonyl)-amino]-thiophene-2-carboxylic acid methyl esterHCID 57795460—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-581e55f513884d5081401bd3af7ba82d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)