Acetic Acid → 4-(2-Amino-ethyl)-1-(2-chloro-benzenesulfonyl)-piperidine-4-carboxylic acid ethyl ester

HRID 1547140Notes

Reaction equation

HRID 1547140 reaction equation
[C:27]([OH:28])(=[O:29])[CH3:30].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1([CH2:22][C:23]#[N:24])[CH2:7][CH2:8][N:9]([S:12](=[O:13])(=[O:14])[c:15]2[c:16]([Cl:21])[cH:17][cH:18][cH:19][cH:20]2)[CH2:10][CH2:11]1.[CH3:25][OH:26]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1([CH2:22][CH2:23][NH2:24])[CH2:7][CH2:8][N:9]([S:12](=[O:13])(=[O:14])[c:15]2[c:16]([Cl:21])[cH:17][cH:18][cH:19][cH:20]2)[CH2:10][CH2:11]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 887MethanolHCID 595780111-(2-Chloro-benzenesulfonyl)-4-cyanomethyl-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 595780964-(2-Amino-ethyl)-1-(2-chloro-benzenesulfonyl)-piperidine-4-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-49d50231404a4591929cade12fc27ec4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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