6-bromo-N2-(quinolin-6-ylmethyl)pyrazine-2,3-diamine → 6-Bromo-N2-(1-(7-fluoroquinolin-6-yl)ethyl)pyrazine-2,3-diamine
Reaction equation
[Br:15][c:16]1[cH:17][n:18][c:19]([NH2:34])[c:20]([NH:22][CH2:23][c:24]2[cH:25][c:26]3[c:27]([cH:28][cH:29]2)[n:30][cH:31][cH:32][cH:33]3)[n:21]1.[F:1][c:2]1[c:3]([CH:12]([CH3:13])[NH2:14])[cH:4][c:5]2[cH:6][cH:7][cH:8][n:9][c:10]2[cH:11]1>>[F:1][c:2]1[c:3]([CH:12]([CH3:13])[NH:14][c:20]2[c:19]([NH2:34])[n:18][cH:17][c:16]([Br:15])[n:21]2)[cH:4][c:5]2[cH:6][cH:7][cH:8][n:9][c:10]2[cH:11]1Participants
3
Sources & evidence
- ORD record
- ord-84e235f2fc0c4021833bf146c07a37a9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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